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KMID : 1197720100030020051
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대한파킨슨병 및 이상운동질환 학회지
2010 Volume.3 No. 2 p.51 ~ p.53
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Preserved Glucose Metabolism of Deep Cerebellar Nuclei in a Case of Multiple System Atrophy with Predominant Cerevellar Ataxia: F-18 Fluorodeoxyglucose Position Emission Tomography Study
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Kwon Oh-Dae
Ki Chang-Seok
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Abstract
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The cerebellar glucose metabolism of multiple system atrophy with predominant cerebellar ataxia (MSA-C) is known to be decreased but is not defined among areas of cerebellum. We encountered a 54-year-old man who developed dizziness and progressive ataxia followed by urinary incontinence and orthostatic hypotension, all of those symptoms progressed relentlessly and the symptoms responded poorly to levodopa therapy. Visual analysis and statistical parametric mapping analysis of F-18 fluorodeoxyglucose positron emission tomography showed hypometabolism of both cerebellar hemisphere, severe at cortical area, and pons. There was clear sparing of deep cerebellar nuclei. Our report, as we know, shows the first case of preserved glucose metabolism of deep cerebellar nuclei relative to cerebellar cortex in an MSA-C patient.
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KEYWORD
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Multiple system atrophy, F-18 Fluorodeoxyglucose position emission tomography, Cerebellar nucleus, Metabolism
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